Title

Candida glabrata endophthalmitis following penetrating keratoplasty

Document Type

Article

Date of Publication

3-2009

Publication Title

Journal of Cataract & Refractive Surgery

First Page

508

Last Page

602

Abstract

We report a case of Candida glabrata endophthalmitis following penetrating keratoplasty in a 57-year-old man. The infection was thought to be treated successfully with intravitreal amphotericin B but flared 7 months later following cataract extraction and eventually required explantation of the intraocular lens and therapeutic keratoplasty. The literature regarding this rare infection is reviewed. Candida glabrata, an uncommon ocular pathogen, is being reported with increasing frequency and with a notable predilection for post-keratoplasty eyes. In the 10 reported cases, there is 100% concordance between host and donor tissue cultures. In half the cases, there was a latent period of several months. These infections can be difficult to treat because C glabrata is often resistant to the antifungal agents commonly used to treat Candida albicans.

Comments

Not to be confused with the 1998 British article of the same name by F. M. Chapman and K. E. Orr. Could be used as a valuable research tool.

DOI

https://doi.org/10.1016/j.jcrs.2008.08.046

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