Transcriptomic Signature and PROTAC Strategy Revealed Histone Lysine Demethylase as a Target of Anticancer Activity of Deferiprone

A. Johnston; J. O.  Olugbami; W. Dipak; B. Wu; R. Kern; Travis Nelson; B. J.  Clarke; J. Murugan; N. A. Hathaway; Y. Fan; A. K.  Oyelere

doi:10.1021/acsomega.5c11926

Transcriptomic Signature and PROTAC Strategy Revealed Histone Lysine Demethylase as a Target of Anticancer Activity of Deferiprone

A. Johnston
, J. O. Olugbami
, W. Dipak
, B. Wu
, R. Kern
, Travis Nelson
, B. J. Clarke
, J. Murugan
, N. A. Hathaway
, Y. Fan
, A. K. Oyelere

Jerry M. Wallace School of Osteopathic Medicine

Research output: Contribution to journal › Article › peer-review

Original language	American English
Pages (from-to)	26421–26437
Journal	ACS Omega
Volume	11
Issue number	18
DOIs	https://doi.org/10.1021/acsomega.5c11926
State	Published - 2026

Access to Document

10.1021/acsomega.5c11926

Cite this

@article{58bbccf2af6c4a07825bd4b74cd73045,

title = "Transcriptomic Signature and PROTAC Strategy Revealed Histone Lysine Demethylase as a Target of Anticancer Activity of Deferiprone",

author = "A. Johnston and Olugbami, \{J. O.\} and W. Dipak and B. Wu and R. Kern and Travis Nelson and Clarke, \{B. J.\} and J. Murugan and Hathaway, \{N. A.\} and Y. Fan and Oyelere, \{A. K.\}",

year = "2026",

doi = "10.1021/acsomega.5c11926",

language = "American English",

volume = "11",

pages = "26421{\textendash}26437",

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number = "18",

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T1 - Transcriptomic Signature and PROTAC Strategy Revealed Histone Lysine Demethylase as a Target of Anticancer Activity of Deferiprone

AU - Johnston, A.

AU - Olugbami, J. O.

AU - Dipak, W.

AU - Wu, B.

AU - Kern, R.

AU - Nelson, Travis

AU - Clarke, B. J.

AU - Murugan, J.

AU - Hathaway, N. A.

AU - Fan, Y.

AU - Oyelere, A. K.

PY - 2026

Y1 - 2026

U2 - 10.1021/acsomega.5c11926

DO - 10.1021/acsomega.5c11926

M3 - Article

C2 - 42146153

VL - 11

SP - 26421

EP - 26437

JO - ACS Omega

JF - ACS Omega

IS - 18

ER -