Synthesis and Structure- Activity Relationships of 5’-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects

R. Vekariya; Wei Lei; A.  Ray; S. Sainai; S. Zhang; G. Molnar; D. Barlow; K. Karlage; E. Bilsky; K. Houseknecht; T. Largent-Milnes; J. Streicher; S. Ananthan

Synthesis and Structure- Activity Relationships of 5’-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects

R. Vekariya
, Wei Lei
, A. Ray
, S. Sainai
, S. Zhang
, G. Molnar
, D. Barlow
, K. Karlage
, E. Bilsky
, K. Houseknecht
, T. Largent-Milnes
, J. Streicher
, S. Ananthan

College of Pharmacy & Health Sciences

Research output: Contribution to journal › Article › peer-review

Original language	American English
Pages (from-to)	7663-7694
Journal	Journal of Medicinal Chemsitry
Volume	63
Issue number	14
State	Published - 2020

Cite this

Vekariya, R., Lei, W., Ray, A., Sainai, S., Zhang, S., Molnar, G., Barlow, D., Karlage, K., Bilsky, E., Houseknecht, K., Largent-Milnes, T., Streicher, J., & Ananthan, S. (2020). Synthesis and Structure- Activity Relationships of 5’-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects. Journal of Medicinal Chemsitry, 63(14), 7663-7694.

Synthesis and Structure- Activity Relationships of 5’-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects. / Vekariya, R.; Lei, Wei; Ray, A. et al.
In: Journal of Medicinal Chemsitry, Vol. 63, No. 14, 2020, p. 7663-7694.

Research output: Contribution to journal › Article › peer-review

Vekariya, R, Lei, W, Ray, A, Sainai, S, Zhang, S, Molnar, G, Barlow, D, Karlage, K, Bilsky, E, Houseknecht, K, Largent-Milnes, T, Streicher, J & Ananthan, S 2020, 'Synthesis and Structure- Activity Relationships of 5’-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects', Journal of Medicinal Chemsitry, vol. 63, no. 14, pp. 7663-7694.

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title = "Synthesis and Structure- Activity Relationships of 5{\textquoteright}-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects",

author = "R. Vekariya and Wei Lei and A. Ray and S. Sainai and S. Zhang and G. Molnar and D. Barlow and K. Karlage and E. Bilsky and K. Houseknecht and T. Largent-Milnes and J. Streicher and S. Ananthan",

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AU - Vekariya, R.

AU - Lei, Wei

AU - Ray, A.

AU - Sainai, S.

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AU - Ananthan, S.

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