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O-GlcNAc modification of transcription factor sp1 mediates hyperglycemia-induced VEGF-A upregulation in retinal cells

  • Kelly Donovan
  • , Oleg Alekseev
  • , Xin Qi
  • , William Cho
  • , Jane Azizkhan-Clifford
  • Drexel University College of Medicine
  • Department of Biochemistry and Molecular Biology
  • The Second Xiangya Hospital of Central South University

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)7862-7873
Number of pages12
JournalInvestigative Ophthalmology and Visual Science
Volume55
Issue number12
DOIs
StatePublished - Oct 28 2014
Externally publishedYes

ASJC Scopus Subject Areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Keywords

  • Diabetic retinopathy
  • O-GlcNAc
  • OGT
  • Sp1
  • VEGF-A

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