Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

Philipp A. Ilinykh; Kai Huang; Rodrigo I. Santos; Pavlo Gilchuk; Bronwyn M. Gunn; Marcus M. Karim; Jenny Liang; Mallorie E. Fouch; Edgar Davidson; Diptiben V. Parekh; James B. Kimble; Colette A. Pietzsch; Michelle Meyer; Natalia A. Kuzmina; Larry Zeitlin; Erica Ollmann Saphire; Galit Alter; James E. Crowe; Alexander Bukreyev

doi:10.1016/j.chom.2020.03.025

Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

Philipp A. Ilinykh
, Kai Huang
, Rodrigo I. Santos
, Pavlo Gilchuk
, Bronwyn M. Gunn
, Marcus M. Karim
, Jenny Liang
, Mallorie E. Fouch
, Edgar Davidson
, Diptiben V. Parekh
, James B. Kimble
, Colette A. Pietzsch
, Michelle Meyer
, Natalia A. Kuzmina
, Larry Zeitlin
, Erica Ollmann Saphire
, Galit Alter
, James E. Crowe
, Alexander Bukreyev

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	976-991.e11
Journal	Cell Host and Microbe
Volume	27
Issue number	6
DOIs	https://doi.org/10.1016/j.chom.2020.03.025
State	Published - Jun 10 2020
Externally published	Yes

ASJC Scopus Subject Areas

Parasitology
Microbiology
Virology

Keywords

animal models of filovirus infection
antibodies
cooperativity of antibody binding
Fc-mediated protective effects
glycoprotein
Marburg virus

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10.1016/j.chom.2020.03.025

Cite this

Ilinykh, P. A., Huang, K., Santos, R. I., Gilchuk, P., Gunn, B. M., Karim, M. M., Liang, J., Fouch, M. E., Davidson, E., Parekh, D. V., Kimble, J. B., Pietzsch, C. A., Meyer, M., Kuzmina, N. A., Zeitlin, L., Saphire, E. O., Alter, G., Crowe, J. E., & Bukreyev, A. (2020). Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host and Microbe, 27(6), 976-991.e11. https://doi.org/10.1016/j.chom.2020.03.025

Ilinykh, PA, Huang, K, Santos, RI, Gilchuk, P, Gunn, BM, Karim, MM, Liang, J, Fouch, ME, Davidson, E, Parekh, DV, Kimble, JB, Pietzsch, CA, Meyer, M, Kuzmina, NA, Zeitlin, L, Saphire, EO, Alter, G, Crowe, JE & Bukreyev, A 2020, 'Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies', Cell Host and Microbe, vol. 27, no. 6, pp. 976-991.e11. https://doi.org/10.1016/j.chom.2020.03.025

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title = "Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies",

keywords = "animal models of filovirus infection, antibodies, cooperativity of antibody binding, Fc-mediated protective effects, glycoprotein, Marburg virus",

author = "Ilinykh, \{Philipp A.\} and Kai Huang and Santos, \{Rodrigo I.\} and Pavlo Gilchuk and Gunn, \{Bronwyn M.\} and Karim, \{Marcus M.\} and Jenny Liang and Fouch, \{Mallorie E.\} and Edgar Davidson and Parekh, \{Diptiben V.\} and Kimble, \{James B.\} and Pietzsch, \{Colette A.\} and Michelle Meyer and Kuzmina, \{Natalia A.\} and Larry Zeitlin and Saphire, \{Erica Ollmann\} and Galit Alter and Crowe, \{James E.\} and Alexander Bukreyev",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = jun,

day = "10",

doi = "10.1016/j.chom.2020.03.025",

language = "English",

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T1 - Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

AU - Ilinykh, Philipp A.

AU - Huang, Kai

AU - Santos, Rodrigo I.

AU - Gilchuk, Pavlo

AU - Gunn, Bronwyn M.

AU - Karim, Marcus M.

AU - Liang, Jenny

AU - Fouch, Mallorie E.

AU - Davidson, Edgar

AU - Parekh, Diptiben V.

AU - Kimble, James B.

AU - Pietzsch, Colette A.

AU - Meyer, Michelle

AU - Kuzmina, Natalia A.

AU - Zeitlin, Larry

AU - Saphire, Erica Ollmann

AU - Alter, Galit

AU - Crowe, James E.

AU - Bukreyev, Alexander

PY - 2020/6/10

Y1 - 2020/6/10

KW - animal models of filovirus infection

KW - antibodies

KW - cooperativity of antibody binding

KW - Fc-mediated protective effects

KW - glycoprotein

KW - Marburg virus

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UR - https://www.scopus.com/pages/publications/85085884760#tab=citedBy

U2 - 10.1016/j.chom.2020.03.025

DO - 10.1016/j.chom.2020.03.025

M3 - Article

C2 - 32320678

AN - SCOPUS:85085884760

SN - 1931-3128

VL - 27

SP - 976-991.e11

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 6

ER -

Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

ASJC Scopus Subject Areas

Keywords

Access to Document

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