African mango (Irvinga gabonensis) extract for weight loss: A systematic review

Objective : The objective of this review is to assess the effectiveness and safety of African mango ( Irvingia gabonensis) extract on weight loss in humans.

Design : A systematic review of articles evaluating the effect of African mango, IGOB131, dikanut, bush mango or Irvingia gabonensis on weight and obesity was conducted.

Population : Three randomized, controlled trials were identified and met criteria for inclusion in the review with a total of 214 subjects receiving Irvingia gabonensis at various doses alone or in combination with other dietary supplements versus placebo over a period of four to ten weeks.

Results : All studies demonstrated a decrease in weight ranging from 4-12kg (p<0.05). Other measures of weight loss including body fat percentage (p<0.05) and waist circumference (p<0.01) were also significantly decreased by Irvingia gabonensis . Improvements were also seen in total cholesterol, low density lipoprotein and fasting blood glucose. Few adverse events were reported but include insomnia, flatulence and headache.

Conclusions : Irvingia gabonensis demonstrates potential for significant weight loss of up to 12 kilograms in overweight and obese subjects over a period of 10 weeks with few reported adverse events. Larger studies including subjects from multiple countries for 6 to 12 months should be conducted to elucidate the long-term effects in various populations.