A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

M. Vedadi; D. Barsyte-Lovejoy; A. Allali-Hassani; V. Labrie; T. J. Wigle; P. A. DiMaggio; G. A. Wasney; A. Siarheyeva; A. Dong; W. Tempel; S-C Wang; X. Chen; I. Chau; T. Mangano; X-P Huang; C. D. Simpson; S. G. Pattenden; J. L. Norris; D. B. Kireev; A. Tripathy; A. Edwards; B. L. Roth; W. P. Janzen; A. B. Garcia; A. Petronis; J. Ellis; P. J. Brown; S. V. Frye; C. H. Arrowsmith; J. Jin

doi:10.1038/nchembio.599

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

M. Vedadi
, D. Barsyte-Lovejoy
, A. Allali-Hassani
, V. Labrie
, T. J. Wigle
, P. A. DiMaggio
, G. A. Wasney
, A. Siarheyeva
, A. Dong
, W. Tempel
, S-C Wang
, X. Chen
, I. Chau
, T. Mangano
, X-P Huang
, C. D. Simpson
, S. G. Pattenden
, J. L. Norris
, D. B. Kireev
, A. Tripathy

A. Edwards, B. L. Roth, W. P. Janzen, A. B. Garcia, A. Petronis, J. Ellis, P. J. Brown, S. V. Frye, C. H. Arrowsmith, J. Jin

Campbell University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Nature Chemical Biology
Volume	7
DOIs	https://doi.org/10.1038/nchembio.599
State	Published - Jan 1 2011

Disciplines

Pharmacy and Pharmaceutical Sciences

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https://pubmed.ncbi.nlm.nih.gov/21743462/

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Vedadi, M., Barsyte-Lovejoy, D., Allali-Hassani, A., Labrie, V., Wigle, T. J., DiMaggio, P. A., Wasney, G. A., Siarheyeva, A., Dong, A., Tempel, W., Wang, S.-C., Chen, X., Chau, I., Mangano, T., Huang, X.-P., Simpson, C. D., Pattenden, S. G., Norris, J. L., Kireev, D. B., ... Jin, J. (2011). A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nature Chemical Biology, 7. https://doi.org/10.1038/nchembio.599

Vedadi, M, Barsyte-Lovejoy, D, Allali-Hassani, A, Labrie, V, Wigle, TJ, DiMaggio, PA, Wasney, GA, Siarheyeva, A, Dong, A, Tempel, W, Wang, S-C, Chen, X, Chau, I, Mangano, T, Huang, X-P, Simpson, CD, Pattenden, SG, Norris, JL, Kireev, DB, Tripathy, A, Edwards, A, Roth, BL, Janzen, WP, Garcia, AB, Petronis, A, Ellis, J, Brown, PJ, Frye, SV, Arrowsmith, CH & Jin, J 2011, 'A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells', Nature Chemical Biology, vol. 7. https://doi.org/10.1038/nchembio.599

@article{5d2fd233b3a5414397d7e58ed7488529,

title = "A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells",

author = "M. Vedadi and D. Barsyte-Lovejoy and A. Allali-Hassani and V. Labrie and Wigle, \{T. J.\} and DiMaggio, \{P. A.\} and Wasney, \{G. A.\} and A. Siarheyeva and A. Dong and W. Tempel and S-C Wang and X. Chen and I. Chau and T. Mangano and X-P Huang and Simpson, \{C. D.\} and Pattenden, \{S. G.\} and Norris, \{J. L.\} and Kireev, \{D. B.\} and A. Tripathy and A. Edwards and Roth, \{B. L.\} and Janzen, \{W. P.\} and Garcia, \{A. B.\} and A. Petronis and J. Ellis and Brown, \{P. J.\} and Frye, \{S. V.\} and Arrowsmith, \{C. H.\} and J. Jin",

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month = jan,

day = "1",

doi = "10.1038/nchembio.599",

language = "American English",

volume = "7",

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TY - JOUR

T1 - A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

AU - Vedadi, M.

AU - Barsyte-Lovejoy, D.

AU - Allali-Hassani, A.

AU - Labrie, V.

AU - Wigle, T. J.

AU - DiMaggio, P. A.

AU - Wasney, G. A.

AU - Siarheyeva, A.

AU - Dong, A.

AU - Tempel, W.

AU - Wang, S-C

AU - Chen, X.

AU - Chau, I.

AU - Mangano, T.

AU - Huang, X-P

AU - Simpson, C. D.

AU - Pattenden, S. G.

AU - Norris, J. L.

AU - Kireev, D. B.

AU - Tripathy, A.

AU - Edwards, A.

AU - Roth, B. L.

AU - Janzen, W. P.

AU - Garcia, A. B.

AU - Petronis, A.

AU - Ellis, J.

AU - Brown, P. J.

AU - Frye, S. V.

AU - Arrowsmith, C. H.

AU - Jin, J.

PY - 2011/1/1

Y1 - 2011/1/1

UR - https://cufind.campbell.edu/pharmacy/2315

UR - https://pubmed.ncbi.nlm.nih.gov/21743462/

U2 - 10.1038/nchembio.599

DO - 10.1038/nchembio.599

M3 - Article

VL - 7

JO - Nature Chemical Biology

JF - Nature Chemical Biology

ER -

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

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