A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

M. Vedadi; D. Barsyte-Lovejoy; A. Allali-Hassani; V. Labrie; T. J. Wigle; P. A. DiMaggio; G. A. Wasney; A. Siarheyeva; A. Dong; W. Tempel; S-C Wang; X. Chen; I. Chau; T. Mangano; X-P Huang; C. D. Simpson; S. G. Pattenden; J. L. Norris; D. B. Kireev; A. Tripathy; A. Edwards; B. L. Roth; W. P. Janzen; A. B. Garcia; A. Petronis; J. Ellis; P. J. Brown; S. V. Frye; C. H. Arrowsmith; J. Jin

doi:10.1038/nchembio.599

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

M. Vedadi, D. Barsyte-Lovejoy, A. Allali-Hassani, V. Labrie, T. J. Wigle, P. A. DiMaggio, G. A. Wasney, A. Siarheyeva, A. Dong, W. Tempel, S-C Wang, X. Chen, I. Chau, T. Mangano, X-P Huang, C. D. Simpson, S. G. Pattenden, J. L. Norris, D. B. Kireev, A. TripathyA. Edwards, B. L. Roth, W. P. Janzen, A. B. Garcia, A. Petronis, J. Ellis, P. J. Brown, S. V. Frye, C. H. Arrowsmith, J. Jin

Campbell University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Nature Chemical Biology
Volume	7
DOIs	https://doi.org/10.1038/nchembio.599
State	Published - Jan 1 2011

Disciplines

Pharmacy and Pharmaceutical Sciences

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https://pubmed.ncbi.nlm.nih.gov/21743462/

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Vedadi, M., Barsyte-Lovejoy, D., Allali-Hassani, A., Labrie, V., Wigle, T. J., DiMaggio, P. A., Wasney, G. A., Siarheyeva, A., Dong, A., Tempel, W., Wang, S.-C., Chen, X., Chau, I., Mangano, T., Huang, X.-P., Simpson, C. D., Pattenden, S. G., Norris, J. L., Kireev, D. B., ... Jin, J. (2011). A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nature Chemical Biology, 7. https://doi.org/10.1038/nchembio.599

Vedadi, M, Barsyte-Lovejoy, D, Allali-Hassani, A, Labrie, V, Wigle, TJ, DiMaggio, PA, Wasney, GA, Siarheyeva, A, Dong, A, Tempel, W, Wang, S-C, Chen, X, Chau, I, Mangano, T, Huang, X-P, Simpson, CD, Pattenden, SG, Norris, JL, Kireev, DB, Tripathy, A, Edwards, A, Roth, BL, Janzen, WP, Garcia, AB, Petronis, A, Ellis, J, Brown, PJ, Frye, SV, Arrowsmith, CH & Jin, J 2011, 'A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells', Nature Chemical Biology, vol. 7. https://doi.org/10.1038/nchembio.599

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title = "A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells",

author = "M. Vedadi and D. Barsyte-Lovejoy and A. Allali-Hassani and V. Labrie and Wigle, {T. J.} and DiMaggio, {P. A.} and Wasney, {G. A.} and A. Siarheyeva and A. Dong and W. Tempel and S-C Wang and X. Chen and I. Chau and T. Mangano and X-P Huang and Simpson, {C. D.} and Pattenden, {S. G.} and Norris, {J. L.} and Kireev, {D. B.} and A. Tripathy and A. Edwards and Roth, {B. L.} and Janzen, {W. P.} and Garcia, {A. B.} and A. Petronis and J. Ellis and Brown, {P. J.} and Frye, {S. V.} and Arrowsmith, {C. H.} and J. Jin",

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doi = "10.1038/nchembio.599",

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T1 - A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

AU - Vedadi, M.

AU - Barsyte-Lovejoy, D.

AU - Allali-Hassani, A.

AU - Labrie, V.

AU - Wigle, T. J.

AU - DiMaggio, P. A.

AU - Wasney, G. A.

AU - Siarheyeva, A.

AU - Dong, A.

AU - Tempel, W.

AU - Wang, S-C

AU - Chen, X.

AU - Chau, I.

AU - Mangano, T.

AU - Huang, X-P

AU - Simpson, C. D.

AU - Pattenden, S. G.

AU - Norris, J. L.

AU - Kireev, D. B.

AU - Tripathy, A.

AU - Edwards, A.

AU - Roth, B. L.

AU - Janzen, W. P.

AU - Garcia, A. B.

AU - Petronis, A.

AU - Ellis, J.

AU - Brown, P. J.

AU - Frye, S. V.

AU - Arrowsmith, C. H.

AU - Jin, J.

PY - 2011/1/1

Y1 - 2011/1/1

UR - https://cufind.campbell.edu/pharmacy/2315

UR - https://pubmed.ncbi.nlm.nih.gov/21743462/

U2 - 10.1038/nchembio.599

DO - 10.1038/nchembio.599

M3 - Article

VL - 7

JO - Nature Chemical Biology

JF - Nature Chemical Biology

ER -

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

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