Projects per year
Personal profile
About
Dr. Rob Hilgers obtained his Ph.D degree in Pharmacology at the University of Maastricht, the Netherlands in 2004. He has substantial postdoctoral research experience in cardiovascular-related diseases conducted at prestigious universities in Europe and the United States. His particular interests involves studying the molecular mechanisms of endothelial dysfunction in resistance arteries in experimental animal models of hypertension, aging and obesity-induced diabetes.His main expertise is the application of myograph systems to assess ex vivo vascular reactivity and structure in correlation with pharmacological interventions. He is particularly interested in the role of endothelial calcium-activated potassium channels in relation to cellular redox status.
Disciplines
- Pharmacy and Pharmaceutical Sciences
Projects
- 3 Active
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Implementation of PK/PD software training for PharmD and Master of Sciences students
Hilgers, R. (PI)
1/1/18 → …
Project: Research project
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Vascular redox control of hyperlipidemia-induced coronary artery dysfunction and atherosclerosis
Hilgers, R. (PI)
1/1/16 → …
Project: Research project
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Effects of Δ9-tetrahydrocannabinol and the aminoalkylindole K2/spice constituent JWH-073 on cardiac tissue and mesenteric vascular reactivity
Breivogel, C. S., Brenseke, B. M., Eldeeb, K., Nichols, K., Jonas, A., Mistry, A. H., Barbalato, L., Luibil, N., Howlett, A. C., Leone-Kabler, S., Hilgers, R. P. & Pulgar, V. M., Apr 3 2023, In: Cannabis and Cannabinoid Research.Research output: Contribution to journal › Article › peer-review
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Decreased EDHF-mediated relaxation is a major mechanism in endothelial dysfunction in resistance arteries in aged mice on prolonged high- fat sucrose diet
Dunn, S. M., Hilgers, R. H. & Das, K. C., Jan 1 2017, In: Physiological Reports. 5Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Thioredoxin reverses age-related hypertension by chronically improving vascular redox and restoring eNOS function
Hilgers, R. H., Kundumani-Sridharan, V., Subramani, J., Chen, L. C., Cuello, L. G., Rusch, N. J. & Das, K. C., Feb 8 2017, In: Science Translational Medicine. 9Research output: Contribution to journal › Article › peer-review
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Thioredoxin uses a GSH-independent route to Deglutathionylate endothelial nitric-oxide synthase and protect against myocardial infarction
Subramani, J., Kundimani-Sridharan, V., Hilgers, R. H., Owens, C. & Das, K. C., Nov 4 2016, In: Journal of Biological Chemistry. 291Research output: Contribution to journal › Article › peer-review
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Role of in vivo vascular redox state in resistance arteries
Hilgers, R. H. & Das, K. C., Jan 1 2015, In: Hypertension. 65Research output: Contribution to journal › Article › peer-review
Activities
- 4 Membership of network
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American Association of Colleges of Pharmacy (External organization)
Hilgers, R. (Member)
2000 → …Activity: Membership › Membership of network
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American Heart Association (External organization)
Hilgers, R. (Member)
2000 → …Activity: Membership › Membership of network
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American Physiological Society (External organization)
Hilgers, R. (Member)
2000 → …Activity: Membership › Membership of network
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American Association for the Advancement of Science (External organization)
Hilgers, R. (Member)
2000 → …Activity: Membership › Membership of network
Prizes
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Graduate Student Travel Award of the American Society for Pharmacology and Experimental Therapeutics (ASPET) at the Experimental Biology ’06, San Francisco, CA, April 1-5, 2006
Hilgers, R. (Recipient), 2006
Prize: Prize (including medals and awards)
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Graduate Student Travel Award of the American Society for Pharmacology and Experimental Therapeutics (ASPET) at the Experimental Biology ’05, San Diego, CA, April 2-6, 2005
Hilgers, R. (Recipient), 2005
Prize: Prize (including medals and awards)
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Young Investigator Award European Council for Blood Pressure and Cardiovascular Research (ECCR), Seeheim, Germany, October 10-12, 2003
Hilgers, R. (Recipient), 2003
Prize: Prize (including medals and awards)
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Pre-doctoral Marie Curie European Fellowship, March 2002-September 2002
Hilgers, R. (Recipient), 2002
Prize: Prize (including medals and awards)
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Graduate Student Travel Award of the American Society for Pharmacology and Experimental Therapeutics (ASPET) at the Experimental Biology ’01, Orlando, FL, March 31-April 4, 2001
Hilgers, R. (Recipient), 2001
Prize: Prize (including medals and awards)